Target

Ligand

Substrate

Meas. Tech.

Thrombin 1536 HTS Dose Response Confirmation

pH

7.5±n/a

Temperature

296.15±n/a K

Citation

 PubChem, PC Thrombin 1536 HTS Dose Response Confirmation PubChem Bioassay (2008)[AID] Copy BDB DOI

More Info.:

Get all data from this article,   Solution Info,  Assay Method

Name:

Prothrombin

Synonyms:

Activation peptide fragment 1 | Activation peptide fragment 2 | Coagulation factor II | F2 | Prothrombin precursor | THRB_HUMAN | Thrombin heavy chain | Thrombin light chain

Type:

Protein

Mol. Mass.:

70029.57

Organism:

Homo sapiens (Human)

Description:

P00734

Residue:

622

Sequence:

MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE

Blast this sequence in BindingDB or PDB

  
Blast E-value cutoff:

Name:

BDBM33481

Synonyms:

3-benzamido-1H-1,2,4-triazole-5-carboxylic acid methyl ester | MLS000564054 | SMR000151640 | cid_2314281 | methyl 3-benzamido-1H-1,2,4-triazole-5-carboxylate

Type:

Small organic molecule

Emp. Form.:

C11H10N4O3

Mol. Mass.:

246.2221

SMILES:

COC(=O)c1nnc(NC(=O)c2ccccc2)[nH]1

Structure:

Search PDB for entries with ligand similarity:

Similarity to this molecule at least:

Name:

Boc-Val-Pro-Arg-AMC

Synonyms:

n/a

Type:

fluorogenic substrate

Mol. Mass.:

358.43

Organism:

n/a

Description:

n/a

Residue:

3

Sequence:

NA