Reaction Details Report a problem with these data
Target
Bcl-2-related protein A1
Ligand
BDBM34171
Substrate
FITC-Ahx-EDIIRNIARHLAQVGDSMDR
Meas. Tech.
HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1
pH
7±n/a
Temperature
296.15±n/a K
IC50
>100000±0 nM
Citation
 PubChem, PC HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM34171
Synonyms:
2-(6-methyl-1,2,3,4-tetrahydrocarbazol-9-yl)acetic acid methyl ester | MLS000039224 | SMR000034295 | cid_658349 | methyl 2-(6-methyl-1,2,3,4-tetrahydrocarbazol-9-yl)acetate | methyl 2-(6-methyl-1,2,3,4-tetrahydrocarbazol-9-yl)ethanoate
Type:
Small organic molecule
Emp. Form.:
C16H19NO2
Mol. Mass.:
257.3276
SMILES:
COC(=O)Cn1c2CCCCc2c2cc(C)ccc12
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
FITC-Ahx-EDIIRNIARHLAQVGDSMDR
Synonyms:
FITC-Bid peptide
Type:
fluorescein-labeled peptide
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA