Target

Ligand

Substrate

Meas. Tech.

In vitro MKP-1 Phosphatase HTS Dose Response Confirmation Assay

pH

7±n/a

Temperature

295.15±n/a K

Citation

 PubChem, PC In vitro MKP-1 Phosphatase HTS Dose Response Confirmation Assay PubChem Bioassay (2007)[AID] Copy BDB DOI

More Info.:

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Name:

Dual specificity protein phosphatase 1

Synonyms:

CL100 | DUS1_HUMAN | DUSP1 | Dual specificity protein phosphatase hVH1 | MAP kinase phosphatase 1 | MKP-1 | MKP1 | PTPN10 | Protein-tyrosine phosphatase CL100 | VH1

Type:

Protein phosphatase

Mol. Mass.:

39301.48

Organism:

Homo sapiens (Human)

Description:

gi_4758204

Residue:

367

Sequence:

MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC

Blast this sequence in BindingDB or PDB

  
Blast E-value cutoff:

Name:

BDBM35377

Synonyms:

MLS000081820 | N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-1,2-oxazole-5-carboxamide | N-[4-(4-methylphenyl)-2-thiazolyl]-5-isoxazolecarboxamide | N-[4-(p-tolyl)thiazol-2-yl]isoxazole-5-carboxamide | SMR000063580 | cid_2999703

Type:

Small organic molecule

Emp. Form.:

C14H11N3O2S

Mol. Mass.:

285.321

SMILES:

Cc1ccc(cc1)-c1csc(NC(=O)c2ccno2)n1

Structure:

Search PDB for entries with ligand similarity:

Similarity to this molecule at least:

Name:

OMFP Substrate

Synonyms:

3-O-methylfluorescein phosphate | OMFP

Type:

fluorescent substrate

Mol. Mass.:

358.43

Organism:

n/a

Description:

n/a

Residue:

3

Sequence:

NA