Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 1
Ligand
BDBM35454
Substrate
OMFP Substrate
Meas. Tech.
In vitro MKP-1 Phosphatase Dose Response SAR Support Assay
pH
7±n/a
Temperature
296.15±n/a K
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-1 Phosphatase Dose Response SAR Support Assay  PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 1
Synonyms:
CL100 | DUS1_HUMAN | DUSP1 | Dual specificity protein phosphatase hVH1 | MAP kinase phosphatase 1 | MKP-1 | MKP1 | PTPN10 | Protein-tyrosine phosphatase CL100 | VH1
Type:
Protein phosphatase
Mol. Mass.:
39301.48
Organism:
Homo sapiens (Human)
Description:
gi_4758204
Residue:
367
Sequence:
MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC
  
Inhibitor
Name:
BDBM35454
Synonyms:
2-cyclopropyl-4-quinolinecarboxylic acid | 2-cyclopropylcinchoninic acid | 2-cyclopropylquinoline-4-carboxylic acid | CC-PMLSC-DMA-P121 | cid_275785
Type:
Small organic molecule
Emp. Form.:
C13H11NO2
Mol. Mass.:
213.2319
SMILES:
OC(=O)c1cc(nc2ccccc12)C1CC1
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
OMFP Substrate
Synonyms:
3-O-methylfluorescein phosphate | OMFP
Type:
fluorescent substrate
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA