Target

Ligand

Substrate

Meas. Tech.

In vitro MKP-1 Phosphatase Dose Response SAR Support Assay

pH

7±n/a

Temperature

296.15±n/a K

Citation

 PubChem, PC In vitro MKP-1 Phosphatase Dose Response SAR Support Assay  PubChem Bioassay (2007)[AID] Copy BDB DOI

More Info.:

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Name:

Dual specificity protein phosphatase 1

Synonyms:

CL100 | DUS1_HUMAN | DUSP1 | Dual specificity protein phosphatase hVH1 | MAP kinase phosphatase 1 | MKP-1 | MKP1 | PTPN10 | Protein-tyrosine phosphatase CL100 | VH1

Type:

Protein phosphatase

Mol. Mass.:

39301.48

Organism:

Homo sapiens (Human)

Description:

gi_4758204

Residue:

367

Sequence:

MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC

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Blast E-value cutoff:

Name:

BDBM35468

Synonyms:

6-amino-1-benzyl-5-(2-chloroacetyl)-3-methyl-pyrimidine-2,4-quinone | 6-amino-1-benzyl-5-(2-chloroacetyl)-3-methylpyrimidine-2,4-dione | 6-amino-5-(2-chloro-1-oxoethyl)-3-methyl-1-(phenylmethyl)pyrimidine-2,4-dione | 6-azanyl-5-(2-chloranylethanoyl)-3-methyl-1-(phenylmethyl)pyrimidine-2,4-dione | CC-PMLSC-DMA-P143 | cid_2392391

Type:

Small organic molecule

Emp. Form.:

C14H14ClN3O3

Mol. Mass.:

307.732

SMILES:

Cn1c(=O)c(C(=O)CCl)c(N)n(Cc2ccccc2)c1=O

Structure:

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Similarity to this molecule at least:

Name:

OMFP Substrate

Synonyms:

3-O-methylfluorescein phosphate | OMFP

Type:

fluorescent substrate

Mol. Mass.:

358.43

Organism:

n/a

Description:

n/a

Residue:

3

Sequence:

NA