Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM30911
Substrate
n/a
Meas. Tech.
S1P3 Agonist Dose-Response Potency Assay
EC50
7180±n/a nM
Citation
 PubChem, PC S1P3 Agonist Dose-Response Potency Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM30911
Synonyms:
7-(2-furoyloxy)-2-keto-chromene-3-carboxylic acid ethyl ester | 7-[2-furanyl(oxo)methoxy]-2-oxo-1-benzopyran-3-carboxylic acid ethyl ester | MLS000050094 | SMR000077133 | cid_733831 | ethyl 7-(2-furoyloxy)-2-oxo-2H-chromene-3-carboxylate | ethyl 7-(furan-2-carbonyloxy)-2-oxochromene-3-carboxylate | ethyl 7-(furan-2-ylcarbonyloxy)-2-oxidanylidene-chromene-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C17H12O7
Mol. Mass.:
328.273
SMILES:
CCOC(=O)c1cc2ccc(OC(=O)c3ccco3)cc2oc1=O
Structure:
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