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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36839
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36839
Synonyms:
3-Methyl-benzofuran-2-carboxylic acid (3-methyl-4-tetrazol-1-yl-phenyl)-amide | 3-methyl-N-[3-methyl-4-(1,2,3,4-tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide | 3-methyl-N-[3-methyl-4-(1-tetrazolyl)phenyl]-2-benzofurancarboxamide | 3-methyl-N-[3-methyl-4-(tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide | 3-methyl-N-[3-methyl-4-(tetrazol-1-yl)phenyl]coumarilamide | MLS000068655 | SMR000003825 | cid_647922
Type:
Small organic molecule
Emp. Form.:
C18H15N5O2
Mol. Mass.:
333.344
SMILES:
Cc1c(oc2ccccc12)C(=O)Nc1ccc(c(C)c1)-n1cnnn1
Structure:
Search PDB for entries with ligand similarity: