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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36844
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
8060±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36844
Synonyms:
1-(3-Fluoro-4-methoxy-phenyl)-3-morpholin-4-yl-2-phenyl-propan-1-one | 1-(3-fluoranyl-4-methoxy-phenyl)-3-morpholin-4-yl-2-phenyl-propan-1-one;hydrochloride | 1-(3-fluoro-4-methoxy-phenyl)-3-morpholino-2-phenyl-propan-1-one;hydrochloride | 1-(3-fluoro-4-methoxyphenyl)-3-(4-morpholinyl)-2-phenyl-1-propanone;hydrochloride | 1-(3-fluoro-4-methoxyphenyl)-3-morpholin-4-yl-2-phenylpropan-1-one;hydrochloride | MLS000035729 | SMR000008712 | cid_3066411
Type:
Small organic molecule
Emp. Form.:
C20H22FNO3
Mol. Mass.:
343.392
SMILES:
COc1ccc(cc1F)C(=O)C(CN1CCOCC1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: