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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36893
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>95100±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36893
Synonyms:
4-[3-(1-benzotriazolyl)-2-hydroxypropoxy]benzoic acid methyl ester | 4-[3-(benzotriazol-1-yl)-2-hydroxy-propoxy]benzoic acid methyl ester | MLS000079871 | SMR000040056 | cid_659056 | methyl 4-[3-(benzotriazol-1-yl)-2-hydroxypropoxy]benzoate | methyl 4-[3-(benzotriazol-1-yl)-2-oxidanyl-propoxy]benzoate
Type:
Small organic molecule
Emp. Form.:
C17H17N3O4
Mol. Mass.:
327.3346
SMILES:
COC(=O)c1ccc(OCC(O)Cn2nnc3ccccc23)cc1
Structure:
Search PDB for entries with ligand similarity: