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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36937
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>95100±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36937
Synonyms:
1-(8-chloro-4-benzofuro[3,2-d]pyrimidinyl)-4-piperidinecarboxylic acid ethyl ester | 1-(8-chlorobenzofuro[3,2-d]pyrimidin-4-yl)isonipecotic acid ethyl ester | MLS000042208 | SMR000045032 | cid_664148 | ethyl 1-(8-chloranyl-[1]benzofuro[3,2-d]pyrimidin-4-yl)piperidine-4-carboxylate | ethyl 1-(8-chloro-[1]benzofuro[3,2-d]pyrimidin-4-yl)piperidine-4-carboxylate
Type:
Small organic molecule
Emp. Form.:
C18H18ClN3O3
Mol. Mass.:
359.807
SMILES:
CCOC(=O)C1CCN(CC1)c1ncnc2c3cc(Cl)ccc3oc12
Structure:
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