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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36961
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>95100±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36961
Synonyms:
5-[(2-fluorobenzyl)amino]-2-morpholino-benzoic acid methyl ester | 5-[(2-fluorophenyl)methylamino]-2-(4-morpholinyl)benzoic acid methyl ester | MLS000039581 | SMR000036012 | cid_667122 | methyl 5-[(2-fluorophenyl)methylamino]-2-morpholin-4-yl-benzoate | methyl 5-[(2-fluorophenyl)methylamino]-2-morpholin-4-ylbenzoate
Type:
Small organic molecule
Emp. Form.:
C19H21FN2O3
Mol. Mass.:
344.38
SMILES:
COC(=O)c1cc(NCc2ccccc2F)ccc1N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: