Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37350
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>49800±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37350
Synonyms:
3-(2,2-Dimethyl-propionylamino)-9-aza-bicyclo[3.3.1]nonane-9-carboxylic acid (2-ethyl-phenyl)-amide | 3-(2,2-dimethylpropanoylamino)-N-(2-ethylphenyl)-9-azabicyclo[3.3.1]nonane-9-carboxamide | 3-[(2,2-dimethyl-1-oxopropyl)amino]-N-(2-ethylphenyl)-9-azabicyclo[3.3.1]nonane-9-carboxamide | MLS000074345 | N-(2-ethylphenyl)-3-(pivaloylamino)-9-azabicyclo[3.3.1]nonane-9-carboxamide | SMR000006250 | cid_644577
Type:
Small organic molecule
Emp. Form.:
C22H33N3O2
Mol. Mass.:
371.5163
SMILES:
[H]C12CCCC([H])(CC(C1)NC(=O)C(C)(C)C)N2C(=O)Nc1ccccc1CC
Structure:
Search PDB for entries with ligand similarity: