Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37392
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>49800±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37392
Synonyms:
MLS000053426 | N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxy-phenyl]-2-(6-methoxy-1-benzofuran-3-yl)ethanamide | N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxy-phenyl]-2-(6-methoxybenzofuran-3-yl)acetamide | N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-2-(6-methoxy-1-benzofuran-3-yl)acetamide | N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-2-(6-methoxy-3-benzofuranyl)acetamide | SMR000063395 | cid_2100172
Type:
Small organic molecule
Emp. Form.:
C24H21FN2O6S
Mol. Mass.:
484.497
SMILES:
COc1ccc2c(CC(=O)Nc3ccc(OC)c(NS(=O)(=O)c4ccc(F)cc4)c3)coc2c1
Structure:
Search PDB for entries with ligand similarity: