Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37475
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>49800±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37475
Synonyms:
MLS000118200 | N-[2-(1-cyclohexenyl)ethyl]-2-[(1,3-dimethyl-2,4-dioxo-6-quinazolinyl)sulfonyl-methylamino]acetamide | N-[2-(cyclohexen-1-yl)ethyl]-2-[(1,3-dimethyl-2,4-dioxoquinazolin-6-yl)sulfonyl-methylamino]acetamide | N-[2-(cyclohexen-1-yl)ethyl]-2-[(2,4-diketo-1,3-dimethyl-quinazolin-6-yl)sulfonyl-methyl-amino]acetamide | N-[2-(cyclohexen-1-yl)ethyl]-2-[[1,3-dimethyl-2,4-bis(oxidanylidene)quinazolin-6-yl]sulfonyl-methyl-amino]ethanamide | SMR000095148 | cid_5308741
Type:
Small organic molecule
Emp. Form.:
C21H28N4O5S
Mol. Mass.:
448.536
SMILES:
CN(CC(=O)NCCC1=CCCCC1)S(=O)(=O)c1ccc2n(C)c(=O)n(C)c(=O)c2c1 |t:8|
Structure:
Search PDB for entries with ligand similarity: