Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37481
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>49800±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37481
Synonyms:
MLS000117448 | N-butyl-6-(dimethylsulfamoyl)-4-keto-N,1-dimethyl-quinoline-3-carboxamide | N-butyl-6-(dimethylsulfamoyl)-N,1-dimethyl-4-oxidanylidene-quinoline-3-carboxamide | N-butyl-6-(dimethylsulfamoyl)-N,1-dimethyl-4-oxo-3-quinolinecarboxamide | N-butyl-6-(dimethylsulfamoyl)-N,1-dimethyl-4-oxoquinoline-3-carboxamide | SMR000094396 | cid_5309484
Type:
Small organic molecule
Emp. Form.:
C18H25N3O4S
Mol. Mass.:
379.474
SMILES:
CCCCN(C)C(=O)c1cn(C)c2ccc(cc2c1=O)S(=O)(=O)N(C)C
Structure:
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