Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37515
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
16640±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37515
Synonyms:
1,4-bis[(4-ethoxyphenyl)sulfonyl]-2-methyl-piperazine | 1,4-bis[(4-ethoxyphenyl)sulfonyl]-2-methylpiperazine | 2-methyl-1,4-bis(p-phenetylsulfonyl)piperazine | MLS000112066 | SMR000107983 | cid_2920901
Type:
Small organic molecule
Emp. Form.:
C21H28N2O6S2
Mol. Mass.:
468.587
SMILES:
CCOc1ccc(cc1)S(=O)(=O)N1CCN(C(C)C1)S(=O)(=O)c1ccc(OCC)cc1
Structure:
Search PDB for entries with ligand similarity: