Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37516
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>49800±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37516
Synonyms:
2-[2-[1-(2-furoyl)-5-methoxy-indol-3-yl]ethyl]isoindoline-1,3-quinone | 2-[2-[1-(furan-2-carbonyl)-5-methoxyindol-3-yl]ethyl]isoindole-1,3-dione | 2-[2-[1-(furan-2-ylcarbonyl)-5-methoxy-indol-3-yl]ethyl]isoindole-1,3-dione | 2-[2-[1-[2-furanyl(oxo)methyl]-5-methoxy-3-indolyl]ethyl]isoindole-1,3-dione | MLS000112238 | SMR000108152 | cid_1162920
Type:
Small organic molecule
Emp. Form.:
C24H18N2O5
Mol. Mass.:
414.4101
SMILES:
COc1ccc2n(cc(CCN3C(=O)c4ccccc4C3=O)c2c1)C(=O)c1ccco1
Structure:
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