Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM37613
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
Ki
3600±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37613
Synonyms:
(4Z)-4-[hydroxy(phenyl)methylene]-1-isobutyl-5-(2-methoxyphenyl)pyrrolidine-2,3-quinone | (4Z)-4-[hydroxy(phenyl)methylidene]-5-(2-methoxyphenyl)-1-(2-methylpropyl)pyrrolidine-2,3-dione | (4Z)-5-(2-methoxyphenyl)-1-(2-methylpropyl)-4-[oxidanyl(phenyl)methylidene]pyrrolidine-2,3-dione | 4-Benzoyl-3-hydroxy-1-isobutyl-5-(2-methoxy-phenyl)-1,5-dihydro-pyrrol-2-one | MLS000029388 | SMR000011234 | cid_5766180
Type:
Small organic molecule
Emp. Form.:
C22H23NO4
Mol. Mass.:
365.4223
SMILES:
COc1ccccc1C1C(C(=O)c2ccccc2)C(=O)C(=O)N1CC(C)C
Structure:
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