Target
fMet-Leu-Phe receptor
Ligand
BDBM37630
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
Ki
12400±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37630
Synonyms:
1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-4-(furan-2-carbonyl)-3-hydroxy-5-thiophen-2-yl-1,5-dihydro-pyrrol-2-one | 1-[2-(3,4-dimethoxyphenyl)ethyl]-3-(furan-2-carbonyl)-4-hydroxy-2-thiophen-2-yl-2H-pyrrol-5-one | 1-[2-(3,4-dimethoxyphenyl)ethyl]-3-(furan-2-ylcarbonyl)-4-oxidanyl-2-thiophen-2-yl-2H-pyrrol-5-one | 1-[2-(3,4-dimethoxyphenyl)ethyl]-3-[2-furanyl(oxo)methyl]-4-hydroxy-2-thiophen-2-yl-2H-pyrrol-5-one | 4-(2-furoyl)-1-homoveratryl-3-hydroxy-5-(2-thienyl)-3-pyrrolin-2-one | MLS000069060 | SMR000013782 | cid_656027
Type:
Small organic molecule
Emp. Form.:
C23H21NO6S
Mol. Mass.:
439.481
SMILES:
COc1ccc(CCN2C(C(C(=O)c3ccco3)C(=O)C2=O)c2cccs2)cc1OC
Structure:
Search PDB for entries with ligand similarity: