Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM37658
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
Ki
19400±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37658
Synonyms:
3-(furan-2-carbonyl)-4-hydroxy-1-[2-(2-hydroxyethoxy)ethyl]-2-[4-hydroxy-3-(methoxymethyl)phenyl]-2H-pyrrol-5-one | 3-(furan-2-ylcarbonyl)-1-[2-(2-hydroxyethyloxy)ethyl]-2-[3-(methoxymethyl)-4-oxidanyl-phenyl]-4-oxidanyl-2H-pyrrol-5-one | 3-[2-furanyl(oxo)methyl]-4-hydroxy-1-[2-(2-hydroxyethoxy)ethyl]-2-[4-hydroxy-3-(methoxymethyl)phenyl]-2H-pyrrol-5-one | 4-(2-furoyl)-3-hydroxy-1-[2-(2-hydroxyethoxy)ethyl]-5-[4-hydroxy-3-(methoxymethyl)phenyl]-3-pyrrolin-2-one | MLS000081316 | SMR000058070 | cid_662399
Type:
Small organic molecule
Emp. Form.:
C21H23NO8
Mol. Mass.:
417.4092
SMILES:
COCc1cc(ccc1O)C1C(C(=O)c2ccco2)C(=O)C(=O)N1CCOCCO
Structure:
Search PDB for entries with ligand similarity: