Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM37744
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
Ki
12100±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37744
Synonyms:
3-[2-(N-ethyl-2,5-dimethoxy-anilino)-2-keto-ethyl]-1H-indole-2-carboxylic acid | 3-[2-(N-ethyl-2,5-dimethoxyanilino)-2-oxoethyl]-1H-indole-2-carboxylic acid | 3-[2-[(2,5-dimethoxyphenyl)-ethyl-amino]-2-oxidanylidene-ethyl]-1H-indole-2-carboxylic acid | 3-{2-[(2,5-dimethoxyphenyl)(ethyl)amino]-2-oxoethyl}-1H-indole-2-carboxylic acid | MLS000044758 | SMR000022868 | cid_3244340
Type:
Small organic molecule
Emp. Form.:
C21H22N2O5
Mol. Mass.:
382.4098
SMILES:
CCN(C(=O)Cc1c([nH]c2ccccc12)C(O)=O)c1cc(OC)ccc1OC
Structure:
Search PDB for entries with ligand similarity: