Target
fMet-Leu-Phe receptor
Ligand
BDBM37806
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
Ki
7600±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37806
Synonyms:
(4Z)-4-[(4-chlorophenyl)-hydroxy-methylene]-5-(5-methyl-2-furyl)-1-(tetrahydrofurfuryl)pyrrolidine-2,3-quinone | (4Z)-4-[(4-chlorophenyl)-hydroxymethylidene]-5-(5-methyl-2-furanyl)-1-(2-oxolanylmethyl)pyrrolidine-2,3-dione | (4Z)-4-[(4-chlorophenyl)-hydroxymethylidene]-5-(5-methylfuran-2-yl)-1-(oxolan-2-ylmethyl)pyrrolidine-2,3-dione | (4Z)-4-[(4-chlorophenyl)-oxidanyl-methylidene]-5-(5-methylfuran-2-yl)-1-(oxolan-2-ylmethyl)pyrrolidine-2,3-dione | MLS000114012 | SMR000109902 | cid_5310704
Type:
Small organic molecule
Emp. Form.:
C21H20ClNO5
Mol. Mass.:
401.84
SMILES:
Cc1ccc(o1)C1C(C(=O)c2ccc(Cl)cc2)C(=O)C(=O)N1CC1CCCO1
Structure:
Search PDB for entries with ligand similarity: