Reaction Details Report a problem with these data
Target
Diphosphomevalonate decarboxylase
Ligand
BDBM38329
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response
IC50
27439±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Diphosphomevalonate decarboxylase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
35571.44
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZN59
Residue:
317
Sequence:
MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYTETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAAGLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEIYPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLKENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMDAGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC
  
Inhibitor
Name:
BDBM38329
Synonyms:
4-methoxy-3-[3-[4-(2-methoxyphenyl)piperazino]propanoylamino]-1H-indole-2-carboxylic acid methyl ester | 4-methoxy-3-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]-1-oxopropyl]amino]-1H-indole-2-carboxylic acid methyl ester | MLS000040529 | SMR000044220 | cid_663451 | methyl 4-methoxy-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propanoylamino]-1H-indole-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C25H30N4O5
Mol. Mass.:
466.5295
SMILES:
COC(=O)c1[nH]c2cccc(OC)c2c1NC(=O)CCN1CCN(CC1)c1ccccc1OC
Structure:
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