Reaction Details Report a problem with these data
Target
Diphosphomevalonate decarboxylase
Ligand
BDBM32096
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response
IC50
9509.5±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Diphosphomevalonate decarboxylase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
35571.44
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZN59
Residue:
317
Sequence:
MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYTETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAAGLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEIYPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLKENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMDAGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC
  
Inhibitor
Name:
BDBM32096
Synonyms:
(6-phenyl-4,5-dihydropyrazolo[4,3-e][1,3]benzothiazol-2-yl)amine | 6-phenyl-4,5-dihydropyrazolo[4,3-e][1,3]benzothiazol-2-amine | 6-phenyl-5,6-dihydro-4H-[1,3]thiazolo[4,5-e]indazol-2-amine | MLS000085948 | SMR000021277 | cid_712700
Type:
Small organic molecule
Emp. Form.:
C14H12N4S
Mol. Mass.:
268.337
SMILES:
Nc1nc-2c(CCc3c-2cnn3-c2ccccc2)s1
Structure:
Search PDB for entries with ligand similarity: