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Target
Dual specificity protein phosphatase 6
Ligand
BDBM35390
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM35390
Synonyms:
2-(2-keto-1-methyl-2-piperidino-ethyl)-4-methyl-benzothiopheno[2,3-d]pyridazin-1-one | 4-methyl-2-(1-methyl-2-oxo-2-piperidin-1-ylethyl)[1]benzothieno[2,3-d]pyridazin-1(2H)-one | 4-methyl-2-(1-oxidanylidene-1-piperidin-1-yl-propan-2-yl)-[1]benzothiolo[2,3-d]pyridazin-1-one | 4-methyl-2-(1-oxo-1-piperidin-1-ylpropan-2-yl)-[1]benzothiolo[2,3-d]pyridazin-1-one | 4-methyl-2-[1-oxo-1-(1-piperidinyl)propan-2-yl]-[1]benzothiolo[2,3-d]pyridazin-1-one | MLS000093662 | SMR000029280 | cid_3238280
Type:
Small organic molecule
Emp. Form.:
C19H21N3O2S
Mol. Mass.:
355.454
SMILES:
CC(C(=O)N1CCCCC1)n1nc(C)c2sc3ccccc3c2c1=O
Structure:
Search PDB for entries with ligand similarity: