Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 6
Ligand
BDBM35397
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM35397
Synonyms:
MLS000095109 | N-cyclopentyl-1-methyl-6-(4-methylpiperidin-1-yl)sulfonyl-4-oxidanylidene-quinoline-3-carboxamide | N-cyclopentyl-1-methyl-6-(4-methylpiperidin-1-yl)sulfonyl-4-oxoquinoline-3-carboxamide | N-cyclopentyl-1-methyl-6-[(4-methyl-1-piperidinyl)sulfonyl]-4-oxo-3-quinolinecarboxamide | N-cyclopentyl-1-methyl-6-[(4-methylpiperidin-1-yl)sulfonyl]-4-oxo-1,4-dihydroquinoline-3-carboxamide | N-cyclopentyl-4-keto-1-methyl-6-(4-methylpiperidino)sulfonyl-quinoline-3-carboxamide | SMR000030663 | cid_3241800
Type:
Small organic molecule
Emp. Form.:
C22H29N3O4S
Mol. Mass.:
431.548
SMILES:
CC1CCN(CC1)S(=O)(=O)c1ccc2n(C)cc(C(=O)NC3CCCC3)c(=O)c2c1
Structure:
Search PDB for entries with ligand similarity: