Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 6
Ligand
BDBM31703
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM31703
Synonyms:
3-(2,5-dimethyl-1-pyrrolyl)benzoic acid | 3-(2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid | 3-(2,5-dimethylpyrrol-1-yl)benzoic acid | MLS000053036 | SMR000068999 | cid_213329
Type:
Small organic molecule
Emp. Form.:
C13H13NO2
Mol. Mass.:
215.2478
SMILES:
Cc1ccc(C)n1-c1cccc(c1)C(O)=O
Structure:
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