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Target
Dual specificity protein phosphatase 6
Ligand
BDBM35421
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM35421
Synonyms:
MLS000065753 | N-[1-(2-oxolanyl)ethyl]-1,3-benzodioxole-5-carboxamide | N-[1-(oxolan-2-yl)ethyl]-1,3-benzodioxole-5-carboxamide | N-[1-(tetrahydro-2-furanyl)ethyl]-1,3-benzodioxole-5-carboxamide | N-[1-(tetrahydrofuryl)ethyl]-piperonylamide | SMR000080431 | cid_2970735
Type:
Small organic molecule
Emp. Form.:
C14H17NO4
Mol. Mass.:
263.2891
SMILES:
CC(NC(=O)c1ccc2OCOc2c1)C1CCCO1
Structure:
Search PDB for entries with ligand similarity: