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Target
Dual specificity protein phosphatase 6
Ligand
BDBM35427
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Hit/Probe Assessment Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM35427
Synonyms:
4-methyl-N-[2-(tosylamino)propyl]benzenesulfonamide | 4-methyl-N-[2-[(4-methylphenyl)sulfonylamino]propyl]benzenesulfonamide | MLS000088806 | N,N'-1,2-propanediylbis(4-methylbenzenesulfonamide) | SMR000071952 | cid_2932603
Type:
Small organic molecule
Emp. Form.:
C17H22N2O4S2
Mol. Mass.:
382.498
SMILES:
CC(CNS(=O)(=O)c1ccc(C)cc1)NS(=O)(=O)c1ccc(C)cc1
Structure:
Search PDB for entries with ligand similarity: