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Target
Mevalonate kinase
Ligand
BDBM38588
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
21203.4±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM38588
Synonyms:
1-(5-esyl-2-hydroxy-phenyl)-3-phenyl-urea | 1-(5-ethylsulfonyl-2-hydroxyphenyl)-3-phenylurea | 1-(5-ethylsulfonyl-2-oxidanyl-phenyl)-3-phenyl-urea | MLS000055727 | SMR000060758 | cid_733062
Type:
Small organic molecule
Emp. Form.:
C15H16N2O4S
Mol. Mass.:
320.364
SMILES:
CCS(=O)(=O)c1ccc(O)c(NC(=O)Nc2ccccc2)c1
Structure:
Search PDB for entries with ligand similarity: