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Target
Dual specificity protein phosphatase 6
Ligand
BDBM35373
Substrate
n/a
Meas. Tech.
In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing
IC50
>50000±n/a nM
Citation
 PubChem, PC In vitro MKP-3 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM35373
Synonyms:
1-butyl-2-[2-(2,4-dimethoxyphenyl)-2-oxidanylidene-ethyl]sulfanyl-benzimidazole-5-sulfonamide | 1-butyl-2-[2-(2,4-dimethoxyphenyl)-2-oxoethyl]sulfanylbenzimidazole-5-sulfonamide | 1-butyl-2-[[2-(2,4-dimethoxyphenyl)-2-keto-ethyl]thio]benzimidazole-5-sulfonamide | 1-butyl-2-[[2-(2,4-dimethoxyphenyl)-2-oxoethyl]thio]-5-benzimidazolesulfonamide | MLS000055142 | SMR000066776 | cid_2997788
Type:
Small organic molecule
Emp. Form.:
C21H25N3O5S2
Mol. Mass.:
463.57
SMILES:
CCCCn1c(SCC(=O)c2ccc(OC)cc2OC)nc2cc(ccc12)S(N)(=O)=O
Structure:
Search PDB for entries with ligand similarity: