Reaction Details Report a problem with these data
Target
M-phase inducer phosphatase 2
Ligand
BDBM38808
Substrate
n/a
Meas. Tech.
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay PubChem Bioassay (2006)[AID] 
Target
Name:
M-phase inducer phosphatase 2
Synonyms:
CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN
Type:
Protein
Mol. Mass.:
64985.27
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
580
Sequence:
MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
  
Inhibitor
Name:
BDBM38808
Synonyms:
1-amino-9a-hydroxy-spiro[6,7,8,9-tetrahydro-5aH-benzo[1,2]thiazolo[3,4-a]pyridine-3,1'-cyclohexane]-2,4-dicarbonitrile | 1-amino-9a-hydroxyspiro[6,7,8,9-tetrahydro-5aH-benzo[1,2][1,3]thiazolo[3,4-a]pyridine-3,1'-cyclohexane]-2,4-dicarbonitrile | 1-amino-9a-hydroxyspiro[6,7,8,9-tetrahydro-5aH-benzo[1,2]thiazolo[3,4-a]pyridine-3,1'-cyclohexane]-2,4-dicarbonitrile | 1-azanyl-9a-oxidanyl-spiro[6,7,8,9-tetrahydro-5aH-benzo[1,2][1,3]thiazolo[3,4-a]pyridine-3,1'-cyclohexane]-2,4-dicarbonitrile | MLS000058429 | SMR000064026 | cid_2999216
Type:
Small organic molecule
Emp. Form.:
C18H22N4OS
Mol. Mass.:
342.458
SMILES:
OC12CCCCC1SC1=C(C#N)C3(CCCCC3)C(C#N)C(=N)N21 |c:9|
Structure:
Search PDB for entries with ligand similarity: