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Target
M-phase inducer phosphatase 2
Ligand
BDBM32334
Substrate
n/a
Meas. Tech.
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay PubChem Bioassay (2006)[AID] 
Target
Name:
M-phase inducer phosphatase 2
Synonyms:
CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN
Type:
Protein
Mol. Mass.:
64985.27
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
580
Sequence:
MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
  
Inhibitor
Name:
BDBM32334
Synonyms:
7-hydroxy-2,3,4,5-tetrahydro-1H-[1]benzofuro[2,3-c]azepin-1-one | 7-hydroxy-2,3,4,5-tetrahydro-[1]benzofuro[2,3-c]azepin-1-one | 7-hydroxy-2,3,4,5-tetrahydrobenzofur[2,3-c]azepin-1-one | 7-hydroxy-2,3,4,5-tetrahydrobenzofuro[2,3-c]azepin-1-one | 7-oxidanyl-2,3,4,5-tetrahydro-[1]benzofuro[2,3-c]azepin-1-one | MLS000043346 | SMR000019965 | cid_755673
Type:
Small organic molecule
Emp. Form.:
C12H11NO3
Mol. Mass.:
217.2206
SMILES:
Oc1ccc2oc3c(CCCNC3=O)c2c1
Structure:
Search PDB for entries with ligand similarity: