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Target
M-phase inducer phosphatase 2
Ligand
BDBM38819
Substrate
n/a
Meas. Tech.
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay
IC50
>50000±n/a nM
Citation
 PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase HTS Dose Response Confirmation Assay PubChem Bioassay (2006)[AID] 
Target
Name:
M-phase inducer phosphatase 2
Synonyms:
CDC25B | CDC25HU2 | Dual specificity phosphatase (CDC25B) | Dual specificity phosphatase Cdc25B | M-phase inducer phosphatase 2 (CDC25B) | MPIP2_HUMAN
Type:
Protein
Mol. Mass.:
64985.27
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
580
Sequence:
MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSKSLCHDEIENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQDQ
  
Inhibitor
Name:
BDBM38819
Synonyms:
MLS000047324 | N-[3-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-1-(4-methoxyphenyl)-3-oxopropyl]-4-fluorobenzenesulfonamide | N-[3-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-1-(4-methoxyphenyl)-3-oxidanylidene-propyl]-4-fluoranyl-benzenesulfonamide | N-[3-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-1-(4-methoxyphenyl)-3-oxopropyl]-4-fluorobenzenesulfonamide | N-[3-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-keto-1-(4-methoxyphenyl)propyl]-4-fluoro-benzenesulfonamide | SMR000033335 | cid_3238230
Type:
Small organic molecule
Emp. Form.:
C23H27FN2O6S
Mol. Mass.:
478.534
SMILES:
COc1ccc(cc1)C(CC(=O)N1CCC2(CC1)OCCO2)NS(=O)(=O)c1ccc(F)cc1
Structure:
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