Target
Bcl-2-related protein A1
Ligand
BDBM39183
Substrate
n/a
Meas. Tech.
TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1
IC50
16400±2040 nM
Citation
 PubChem, PC TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM39183
Synonyms:
3,4-bis(chloranyl)-1-(3-nitrophenyl)pyrrole-2,5-dione | 3,4-dichloro-1-(3-nitrophenyl)-3-pyrroline-2,5-quinone | 3,4-dichloro-1-(3-nitrophenyl)pyrrole-2,5-dione | MLS-0111858.0001 | cid_1590141
Type:
Small organic molecule
Emp. Form.:
C10H4Cl2N2O4
Mol. Mass.:
287.056
SMILES:
[O-][N+](=O)c1cccc(c1)N1C(=O)C(Cl)=C(Cl)C1=O |t:14|
Structure:
Search PDB for entries with ligand similarity: