Reaction Details Report a problem with these data
Target
Coagulation factor XI
Ligand
BDBM32662
Substrate
n/a
Meas. Tech.
Factor XIa Dose Response Confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Factor XIa Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Coagulation factor XI
Synonyms:
Coagulation factor XIa | Coagulation factor XIa heavy chain | Coagulation factor XIa light chain | F11 | FA11_HUMAN | FXI | Factor XIa | Factor XIa (fXIa) | PTA | Plasma thromboplastin antecedent
Type:
Enzyme
Mol. Mass.:
70130.58
Organism:
Homo sapiens (Human)
Description:
P03951
Residue:
625
Sequence:
MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLFTFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRITKLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFFTFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV
  
Inhibitor
Name:
BDBM32662
Synonyms:
MLS000074201 | N,N-Dicyclohexyl-2-(1-methyl-1H-tetrazol-5-ylsulfanyl)-acetamide | N,N-dicyclohexyl-2-(1-methyltetrazol-5-yl)sulfanylacetamide | N,N-dicyclohexyl-2-[(1-methyl-1,2,3,4-tetrazol-5-yl)sulfanyl]ethanamide | N,N-dicyclohexyl-2-[(1-methyl-5-tetrazolyl)thio]acetamide | N,N-dicyclohexyl-2-[(1-methyltetrazol-5-yl)thio]acetamide | SMR000005390 | cid_650164
Type:
Small organic molecule
Emp. Form.:
C16H27N5OS
Mol. Mass.:
337.483
SMILES:
Cn1nnnc1SCC(=O)N(C1CCCCC1)C1CCCCC1
Structure:
Search PDB for entries with ligand similarity: