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Target
Alkaline phosphatase, germ cell type
Ligand
BDBM34696
Substrate
n/a
Meas. Tech.
Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase
IC50
10200±1250 nM
Citation
 PubChem, PC Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase PubChem Bioassay (2007)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM34696
Synonyms:
2-Amino-3-(3,4-dihydroxy-phenyl)-propionic acid methyl ester | 2-amino-3-(3,4-dihydroxyphenyl)propanoic acid methyl ester;hydrochloride | 2-amino-3-(3,4-dihydroxyphenyl)propionic acid methyl ester;hydrochloride | MLS000551310 | SMR000145236 | cid_9551841 | methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate;hydrochloride | methyl 2-azanyl-3-[3,4-bis(oxidanyl)phenyl]propanoate;hydrochloride
Type:
Small organic molecule
Emp. Form.:
C10H13NO4
Mol. Mass.:
211.2145
SMILES:
COC(=O)C(N)Cc1ccc(O)c(O)c1
Structure:
Search PDB for entries with ligand similarity: