Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM39426
Substrate
n/a
Meas. Tech.
Dose-response cell-based assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1)
EC50
183±n/a nM
Citation
 PubChem, PC Dose-response cell-based assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM39426
Synonyms:
7-amino-3-phenyl-6-pyrazolo[1,5-a]pyrimidinecarboxylic acid ethyl ester | 7-amino-3-phenyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester | MLS000075211 | SMR000014414 | cid_649053 | ethyl 7-amino-3-phenylpyrazolo[1,5-a]pyrimidine-6-carboxylate | ethyl 7-azanyl-3-phenyl-pyrazolo[1,5-a]pyrimidine-6-carboxylate
Type:
Small organic molecule
Emp. Form.:
C15H14N4O2
Mol. Mass.:
282.2973
SMILES:
CCOC(=O)c1cnc2c(cnn2c1N)-c1ccccc1
Structure:
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