Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM37007
Substrate
n/a
Meas. Tech.
Dose-response cell-based assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1)
EC50
477±n/a nM
Citation
 PubChem, PC Dose-response cell-based assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM37007
Synonyms:
2-methyl-6-phenyl-3-(1-pyrrolyl)-4-thieno[2,3-d]pyrimidinone | 2-methyl-6-phenyl-3-pyrrol-1-yl-thieno[2,3-d]pyrimidin-4-one | 2-methyl-6-phenyl-3-pyrrol-1-ylthieno[2,3-d]pyrimidin-4-one | MLS000054603 | SMR000061384 | cid_1228645
Type:
Small organic molecule
Emp. Form.:
C17H13N3OS
Mol. Mass.:
307.37
SMILES:
Cc1nc2sc(cc2c(=O)n1-n1cccc1)-c1ccccc1
Structure:
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