Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM38393
Substrate
n/a
Meas. Tech.
Dose-response cell-based assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1)
EC50
>99000±n/a nM
Citation
 PubChem, PC Dose-response cell-based assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM38393
Synonyms:
MLS000046703 | N-(2-oxolanylmethyl)-3-furo[3,2-b]quinoxalinecarboxamide | N-(oxolan-2-ylmethyl)furo[3,2-b]quinoxaline-3-carboxamide | N-(tetrahydrofuran-2-ylmethyl)furo[2,3-b]quinoxaline-3-carboxamide | N-(tetrahydrofurfuryl)furo[3,2-b]quinoxaline-3-carboxamide | SMR000032714 | cid_3237531
Type:
Small organic molecule
Emp. Form.:
C16H15N3O3
Mol. Mass.:
297.3086
SMILES:
O=C(NCC1CCCO1)c1coc2nc3ccccc3nc12
Structure:
Search PDB for entries with ligand similarity: