Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM33610
Substrate
n/a
Meas. Tech.
Dose-response cell-based assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1)
EC50
11260±n/a nM
Citation
 PubChem, PC Dose-response cell-based assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM33610
Synonyms:
1-[5-(2-furanylmethylamino)-3-phenyl-1,2,4-triazol-1-yl]-2-phenylethanone | 1-[5-(2-furfurylamino)-3-phenyl-1,2,4-triazol-1-yl]-2-phenyl-ethanone | 1-[5-(furan-2-ylmethylamino)-3-phenyl-1,2,4-triazol-1-yl]-2-phenyl-ethanone | 1-[5-(furan-2-ylmethylamino)-3-phenyl-1,2,4-triazol-1-yl]-2-phenylethanone | MLS000115577 | SMR000092653 | cid_3896375
Type:
Small organic molecule
Emp. Form.:
C21H18N4O2
Mol. Mass.:
358.3932
SMILES:
O=C(Cc1ccccc1)n1nc(nc1NCc1ccco1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: