Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM39520
Substrate
n/a
Meas. Tech.
Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1)
EC50
>1222±n/a nM
Citation
 PubChem, PC Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM39520
Synonyms:
2-(2-Fluoro-benzylsulfanyl)-3-methyl-3H-imidazo[4,5-b]pyridine | 2-[(2-fluorobenzyl)thio]-3-methyl-imidazo[4,5-b]pyridine | 2-[(2-fluorophenyl)methylsulfanyl]-3-methyl-imidazo[4,5-b]pyridine | 2-[(2-fluorophenyl)methylsulfanyl]-3-methylimidazo[4,5-b]pyridine | 2-[(2-fluorophenyl)methylthio]-3-methylimidazo[4,5-b]pyridine | MLS000073602 | SMR000006767 | cid_649231
Type:
Small organic molecule
Emp. Form.:
C14H12FN3S
Mol. Mass.:
273.329
SMILES:
Cn1c(SCc2ccccc2F)nc2cccnc12
Structure:
Search PDB for entries with ligand similarity: