Target
Steroidogenic factor 1
Ligand
BDBM39521
Substrate
n/a
Meas. Tech.
Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1)
EC50
3284±n/a nM
Citation
 PubChem, PC Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM39521
Synonyms:
(3-Cyano-7-ethoxy-quinolin-2-ylsulfanyl)-acetic acid ethyl ester | 2-[(3-cyano-7-ethoxy-2-quinolinyl)thio]acetic acid ethyl ester | 2-[(3-cyano-7-ethoxy-2-quinolyl)thio]acetic acid ethyl ester | MLS000032271 | SMR000002489 | cid_650479 | ethyl 2-(3-cyano-7-ethoxy-quinolin-2-yl)sulfanylethanoate | ethyl 2-(3-cyano-7-ethoxyquinolin-2-yl)sulfanylacetate
Type:
Small organic molecule
Emp. Form.:
C16H16N2O3S
Mol. Mass.:
316.375
SMILES:
CCOC(=O)CSc1nc2cc(OCC)ccc2cc1C#N
Structure:
Search PDB for entries with ligand similarity: