Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM39541
Substrate
n/a
Meas. Tech.
Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1)
EC50
4109±n/a nM
Citation
 PubChem, PC Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM39541
Synonyms:
MLS000041618 | N-[2-(5-bromanylfuran-2-yl)-3H-benzimidazol-5-yl]thiophene-2-carboxamide | N-[2-(5-bromo-2-furanyl)-3H-benzimidazol-5-yl]-2-thiophenecarboxamide | N-[2-(5-bromo-2-furyl)-3H-benzimidazol-5-yl]thiophene-2-carboxamide | N-[2-(5-bromofuran-2-yl)-3H-benzimidazol-5-yl]thiophene-2-carboxamide | SMR000046012 | cid_664956
Type:
Small organic molecule
Emp. Form.:
C16H10BrN3O2S
Mol. Mass.:
388.239
SMILES:
Brc1ccc(o1)-c1nc2ccc(NC(=O)c3cccs3)cc2[nH]1
Structure:
Search PDB for entries with ligand similarity: