Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM39553
Substrate
n/a
Meas. Tech.
Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1)
EC50
>11000±n/a nM
Citation
 PubChem, PC Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM39553
Synonyms:
3-(2-amino-4,5-dimethyl-anilino)-5,5-dimethyl-cyclohex-2-en-1-one | 3-(2-amino-4,5-dimethylanilino)-5,5-dimethyl-1-cyclohex-2-enone | 3-(2-amino-4,5-dimethylanilino)-5,5-dimethylcyclohex-2-en-1-one | 3-[(2-amino-4,5-dimethylphenyl)amino]-5,5-dimethylcyclohex-2-en-1-one | 3-[(2-azanyl-4,5-dimethyl-phenyl)amino]-5,5-dimethyl-cyclohex-2-en-1-one | MLS000043011 | SMR000019438 | cid_3242790
Type:
Small organic molecule
Emp. Form.:
C16H22N2O
Mol. Mass.:
258.3587
SMILES:
Cc1cc(N)c(NC2=CC(=O)CC(C)(C)C2)cc1C |t:7|
Structure:
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