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Target
14-3-3 protein gamma
Ligand
BDBM32074
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
852.7±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM32074
Synonyms:
1-ethyl-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylsulfanylmethyl)benzimidazole-5-carboxylic acid | 1-ethyl-2-[([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)methyl]-5-benzimidazolecarboxylic acid | 1-ethyl-2-[([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)methyl]benzimidazole-5-carboxylic acid | MLS000058049 | SMR000067059 | cid_2123860
Type:
Small organic molecule
Emp. Form.:
C17H15N5O2S
Mol. Mass.:
353.398
SMILES:
CCn1c(CSc2nnc3ccccn23)nc2cc(ccc12)C(O)=O
Structure:
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