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Target
14-3-3 protein gamma
Ligand
BDBM32090
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
8916.9±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM32090
Synonyms:
1-ethyl-4-keto-6-piperidinosulfonyl-N-(2-pyridylmethyl)quinoline-3-carboxamide | 1-ethyl-4-oxidanylidene-6-piperidin-1-ylsulfonyl-N-(pyridin-2-ylmethyl)quinoline-3-carboxamide | 1-ethyl-4-oxo-6-(1-piperidinylsulfonyl)-N-(2-pyridinylmethyl)-3-quinolinecarboxamide | 1-ethyl-4-oxo-6-(piperidin-1-ylsulfonyl)-N-(pyridin-2-ylmethyl)-1,4-dihydroquinoline-3-carboxamide | 1-ethyl-4-oxo-6-piperidin-1-ylsulfonyl-N-(pyridin-2-ylmethyl)quinoline-3-carboxamide | MLS000095116 | SMR000030670 | cid_3240783
Type:
Small organic molecule
Emp. Form.:
C23H26N4O4S
Mol. Mass.:
454.542
SMILES:
CCn1cc(C(=O)NCc2ccccn2)c(=O)c2cc(ccc12)S(=O)(=O)N1CCCCC1
Structure:
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