Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM40440
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)
Ki
>40300±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)  PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM40440
Synonyms:
2-(4-chlorophenyl)-4-hydroxy-1-(2-phenylethyl)-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one | 2-(4-chlorophenyl)-4-hydroxy-3-[oxo(thiophen-2-yl)methyl]-1-(2-phenylethyl)-2H-pyrrol-5-one | 2-(4-chlorophenyl)-4-oxidanyl-1-(2-phenylethyl)-3-thiophen-2-ylcarbonyl-2H-pyrrol-5-one | 5-(4-chlorophenyl)-3-hydroxy-1-phenethyl-4-(2-thenoyl)-3-pyrrolin-2-one | UNM000003599701 | cid_3880689
Type:
Small organic molecule
Emp. Form.:
C23H18ClNO3S
Mol. Mass.:
423.912
SMILES:
Clc1ccc(cc1)C1C(C(=O)c2cccs2)C(=O)C(=O)N1CCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: