Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM40452
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)
Ki
>40300±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)  PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM40452
Synonyms:
3-(4-methoxyphenyl)-2-methyl-4-(3-methylpiperidin-1-yl)carbonyl-3,4-dihydroisoquinolin-1-one | 3-(4-methoxyphenyl)-2-methyl-4-(3-methylpiperidine-1-carbonyl)-3,4-dihydroisocarbostyril | 3-(4-methoxyphenyl)-2-methyl-4-(3-methylpiperidine-1-carbonyl)-3,4-dihydroisoquinolin-1-one | 3-(4-methoxyphenyl)-2-methyl-4-[(3-methyl-1-piperidinyl)-oxomethyl]-3,4-dihydroisoquinolin-1-one | UNM000003608701 | cid_4147889
Type:
Small organic molecule
Emp. Form.:
C24H28N2O3
Mol. Mass.:
392.4907
SMILES:
COc1ccc(cc1)C1C(C(=O)N2CCCC(C)C2)c2ccccc2C(=O)N1C
Structure:
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