Target
N-formyl peptide receptor 2
Ligand
BDBM40416
Substrate
n/a
Meas. Tech.
Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)
IC50
>66700±n/a nM
Citation
 PubChem, PC Formylpeptide Receptor (FPR) Ligand Structure Activity Relationship (SAR) Analysis : Dose Response Assay Counterscreen Against Formyl Peptide Receptor-Like-1 (FPRL1)  PubChem Bioassay (2007)[AID] 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM40416
Synonyms:
2-thiophenecarboxylic acid [3-(2-chlorophenyl)-4-oxo-2-(trifluoromethyl)-1-benzopyran-7-yl] ester | UNM000003547001 | [3-(2-chlorophenyl)-4-oxidanylidene-2-(trifluoromethyl)chromen-7-yl] thiophene-2-carboxylate | [3-(2-chlorophenyl)-4-oxo-2-(trifluoromethyl)chromen-7-yl] thiophene-2-carboxylate | cid_1561677 | thiophene-2-carboxylic acid [3-(2-chlorophenyl)-4-keto-2-(trifluoromethyl)chromen-7-yl] ester
Type:
Small organic molecule
Emp. Form.:
C21H10ClF3O4S
Mol. Mass.:
450.815
SMILES:
FC(F)(F)c1oc2cc(OC(=O)c3cccs3)ccc2c(=O)c1-c1ccccc1Cl |(4.41,2.51,;5.75,1.74,;6.52,3.08,;4.98,.41,;7.08,.97,;8.41,1.74,;9.75,.97,;11.13,1.8,;12.52,1,;13.85,1.78,;15.19,1.01,;15.19,-.53,;16.52,1.79,;17.93,1.17,;18.95,2.32,;18.18,3.65,;16.67,3.32,;12.52,-.6,;11.13,-1.39,;9.75,-.57,;8.41,-1.34,;8.41,-2.88,;7.08,-.57,;5.75,-1.34,;4.41,-.57,;3.08,-1.34,;3.08,-2.88,;4.41,-3.65,;5.75,-2.88,;7.08,-3.65,)|
Structure:
Search PDB for entries with ligand similarity: